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PDE5 Inhibition

Showing 1 - 25 of 9,912
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
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Cystic Fibrosis Trial in Denver, Augusta (Sildenafil 40mg oral capsule, Placebo Oral capsule)

Recruiting
  • Cystic Fibrosis
  • Sildenafil 40mg oral capsule
  • Placebo Oral capsule
  • Denver, Colorado
  • +1 more
Aug 29, 2022

Healthy, Obese Trial in Nashville (Tadalafil, Placebo)

Completed
Has Results
  • Healthy
  • Obese
  • Nashville, Tennessee
    Vanderbilt University Medical Center
May 3, 2022

Obesity Trial in Nashville (Tadalafil 20 MG, Placebo)

Recruiting
  • Obesity
  • Tadalafil 20 MG
  • Placebo
  • Nashville, Tennessee
    Vanderbilt University Medical Center
Mar 29, 2022

Head and Neck Squamous Cell Carcinoma, Head Neck Cancer Trial in Miami (drug, biological, other)

Completed
  • Head and Neck Squamous Cell Carcinoma
  • Head and Neck Cancer
  • Miami, Florida
    University of Miami
Jun 10, 2021

Seborrheic Dermatitis, Papulopustular Rosacea Trial in New York (PF-07038124, Placebo Ointment)

Recruiting
  • Seborrheic Dermatitis
  • Papulopustular Rosacea
  • New York, New York
    Icahn School of Medicine at Mount Sinai
Aug 22, 2023

Type 2 Diabetes Trial in Göteborg (Tadalafil)

Terminated
  • Type 2 Diabetes
  • Göteborg, Sweden
    The Wallenberg Laboratory, Dept of Molecular and Clinical Medici
Feb 10, 2020

Heart Failure With Preserved Ejection Fraction Trial (IMR-687, IMR-687 Placebo)

Withdrawn
  • Heart Failure With Preserved Ejection Fraction
  • (no location specified)
May 23, 2022

Chronic Plaque Psoriasis Trial in Canada, United States (ARQ-151 0.3% cream, ARQ-151 vehicle cream)

Completed
Has Results
  • Chronic Plaque Psoriasis
  • Roflumilast 0.3% cream
  • Vehicle Cream
  • Encinitas, California
  • +39 more
Dec 5, 2022

Cardiac Allograft Vasculopathy Trial in Minneapolis (Sildenafil, Placebo)

Withdrawn
  • Cardiac Allograft Vasculopathy
  • Minneapolis, Minnesota
    University of Minnesota Medical Center
Oct 30, 2019

Erectile Dysfunction Trial in Saint Petersburg (PDE5 inhibitor (tadalafil) and BTL-6000 fSWT, PDE5 inhibitor (tadalafil))

Recruiting
  • Erectile Dysfunction
  • PDE5 inhibitor (tadalafil) and BTL-6000 fSWT
  • PDE5 inhibitor (tadalafil)
  • Saint Petersburg, Russian Federation
    SBPSU
Apr 10, 2023

Heart Defects, Congenital, Transposition of Great Vessels With Ventricular Inversion Trial in Austria, Switzerland (Tadalafil 20

Completed
  • Heart Defects, Congenital
  • Transposition of Great Vessels With Ventricular Inversion
  • Tadalafil 20 MG
  • Placebo 20 MG
  • Wien, Austria
  • +6 more
Feb 23, 2022

Post-Traumatic Headache Trial (Sildenafil, Placebo)

Not yet recruiting
  • Post-Traumatic Headache
  • (no location specified)
Dec 20, 2022

ive Alzheimer's Medicines - PDE5 Inhibitors vs Endothelin

Active, not recruiting
  • Pulmonary Arterial Hypertension
  • PDE5 inhibitor
  • Endothelin Receptor Antagonists
  • Boston, Massachusetts
    Brigham and Women's Hospital
Nov 15, 2021

Breast Cancer Trial in Ottawa, Toronto (Arm A: Cemiplimab, Arm B: Cemiplimab + Dupilumab)

Not yet recruiting
  • Breast Cancer
  • Arm A: Cemiplimab, Arm B: Cemiplimab + Dupilumab
  • Ottawa, Ontario, Canada
  • +1 more
Jul 22, 2023

Seborrheic Dermatitis Trial in Canada, United States (ARQ-154 - Active, ARQ-154 Vehicle)

Completed
  • Seborrheic Dermatitis
  • ARQ-154 - Active
  • ARQ-154 Vehicle
  • Scottsdale, Arizona
  • +52 more
Aug 4, 2022

Aging, Insulin Resistance Trial in Madison (Everolimus 0.5 MG once per day, Everolimus 5 MG once per week, Placebo once per day)

Recruiting
  • Aging
  • Insulin Resistance
  • Everolimus 0.5 MG once per day
  • +3 more
  • Madison, Wisconsin
    University of Wisconsin-Madison
Apr 19, 2023

Underlying Conditions in Men Prescribed a PDE5 Inhibitor

Completed
Has Results
  • Erectile Dysfunction
  • +2 more
  • no intervention
  • (no location specified)
Jul 15, 2021

Atopic Dermatitis Eczema Trial in Canada, United States (ARQ-151 Active, ARQ-151 Vehicle)

Active, not recruiting
  • Atopic Dermatitis Eczema
  • ARQ-151 Active
  • ARQ-151 Vehicle
  • Montgomery, Alabama
  • +48 more
Aug 10, 2022

Sars-CoV-2 Infection Trial in Bydgoszcz (Evolocumab, Saline solution)

Completed
  • Sars-CoV-2 Infection
  • Bydgoszcz, Poland
    Antoni Jurasz University Hospital No. 1
Dec 14, 2022

Atopic Dermatitis Eczema Trial in Canada, United States (ARQ-151 Active, ARQ-151 Vehicle Cream)

Recruiting
  • Atopic Dermatitis Eczema
  • ARQ-151 Active
  • ARQ-151 Vehicle Cream
  • Birmingham, Alabama
  • +52 more
Aug 4, 2022

Retinitis Pigmentosa Trial in Nantes (AAV2/5-hPDE6B)

Active, not recruiting
  • Retinitis Pigmentosa
  • AAV2/5-hPDE6B
  • Nantes, France
    Clinique Ophtalmologique, CHU de Nantes
Feb 28, 2022

Metastatic Colorectal Cancer, MSS Trial in Heidelberg (Pembrolizumab, Maraviroc)

Completed
Has Results
  • Metastatic Colorectal Cancer
  • MSS
  • Heidelberg, Germany
    National Center for Tumor Diseases, University Hospital Heidelbe
May 17, 2022

Alzheimer, Mild Cognitive Impairment Trial in Boca Raton, New York, Madison (Placebo, Eligard 22.5Mg Suspension for Injection)

Recruiting
  • Alzheimer Disease
  • Mild Cognitive Impairment
  • Placebo
  • Eligard 22.5Mg Suspension for Injection
  • Boca Raton, Florida
  • +2 more
Jan 24, 2023

Erectile Dysfunction Following Radiation Therapy, Phosphodiesterase Inhibitor Adverse Reaction, Platelet- Rich Plasma (PRP)

Active, not recruiting
  • Erectile Dysfunction Following Radiation Therapy
  • +2 more
  • P shot arm ( Autologous Platelet Rich Plasma)
  • PDE5i arm
  • Mansoura, Outside U.S./Canada, Egypt
    Mansoura urology and nephrology center
Mar 15, 2023

Chronic Plaque Psoriasis Trial in Canada, United States (Topical roflumilast)

Enrolling by invitation
  • Chronic Plaque Psoriasis
  • Topical roflumilast
  • Beverly Hills, California
  • +68 more
Nov 9, 2022